Consult your doctor if you are unsure whether a medication or supplement is safe. Ibuprofen is not considered safe during pregnancy, and Aspirin should be avoided (unless directed by your doctor). Some herbal supplements such as Echinacea, Ginkgo Biloba, and St. John’s Wort can interfere with conception. It is best to consult with your doctor about all medications you are on while trying to conceive.